کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5588590 | 1569106 | 2017 | 30 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Post-prandial systemic 8-isoprostane increases after consumption of moderate and high-fat meals in insufficiently active males
ترجمه فارسی عنوان
8-ایزوپروستان سیستمیک پس از زایمان پس از مصرف وعده های غذایی متوسط و با چربی در مردان ناکافی فعال می شود
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کلمات کلیدی
HFMPPLIAUCEBCMFMAUC - AUCTAS - IAScardiovascular disease - بیماری قلب و عروقیanalysis of variance - تحلیل واریانسANOVA - تحلیل واریانس Analysis of varianceTriglycerides - تریگلیسریدOxidative stress - تنش اکسیداتیوCardiovascular disease risk - خطر بیماری قلبی عروقیCVD - رسوب دهی شیمیایی بخار Postprandial lipemia - لیپمی پس از سزارینExhaled breath condensate - مایع مایع نفس کشیدنincremental area under the curve - منطقه افزایشی زیر منحنیarea under the curve - منطقه تحت منحنیTotal antioxidant status - وضعیت آنتی اکسیدان کلHigh-fat meal - وعده غذایی با چربی زیاد
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
چکیده انگلیسی
A single high-fat meal (HFM) leads to an increase in triglycerides and oxidative stress. Oxidative stress can be assessed via 8-isoprostane generation, which is associated with the development of asthma and cardiovascular disease. No previous research has investigated whether airway and systemic 8-isoprostane increases postprandially in nonasthmatic participants according to the energy and fat content of a meal. Our purpose was to assess airway and systemic 8-isoprostane after a HFM and a true-to-life moderate-fat meal (MFM). We hypothesized that airway and systemic 8-isoprostane would increase after a HFM and a MFM, with the greatest increase in the HFM condition. Eight nonasthmatic men (25.8 ± 6.9 years) completed the HFM and MFM trials in a randomized crossover design. After a 10-hour fast, participants consumed either a HFM (71.13 kJ/kg body mass, 60% fat, 23% CHO) or a MFM (35.56 kJ/kg body mass, 30% fat, 52% CHO). Exhaled breath condensate to assess airway 8-isoprostane was collected at baseline and at 3 and 6 hours postmeal. Venous blood samples were collected at baseline and hourly until 6 hours postmeal to assess triglycerides, and every 3 hours for systemic 8-isoprostane. Airway 8-isoprostane responses were not significant as a main effect of time (P = .072), between conditions (P = .365), or between time and condition (P = .319) postmeal. Systemic 8-isoprostane increased over time (P < .001), but not between conditions (P = .124) or between time and condition (P = .649) postmeal. Triglyceride incremental area under the curve was different in the HFM compared to the MFM condition (P = .013). After a HFM and a MFM, 8-isoprostane increases systemically; however, airway 8-isoprostane does not change.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition Research - Volume 39, March 2017, Pages 61-68
Journal: Nutrition Research - Volume 39, March 2017, Pages 61-68
نویسندگان
S.P. Kurti, S.R. Emerson, S.K. Rosenkranz, C.S. Teeman, E.M. Emerson, B.J. Cull, J.R. Smith, C.A. Harms,