کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5589822 | 1569836 | 2017 | 16 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Comparative transcriptomic analyses of male and female adult Toxocara canis
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کلمات کلیدی
RdRpdumpyDpyregulator of chromosome condensation 1NELL2NEDD8Carboxylesterase 1Toxocara canisCEHRCC1SH3HHEXBTBMOSCSRCRNRhoARASALGETsSCFCCR4ras homolog gene family, member A - ras homolog gene family، عضو AElk-1 - الک-1Transcriptome - ترانسکریپتومRaspberry - تمشکReproduction - تولید مثل یا زادآوریDevelopment - رشدEclosion hormone - هورمون EclosionNuclear hormone receptor - گیرنده هورمون هسته ای
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Toxocariasis is an important, neglected zoonosis caused mainly by Toxocara canis. Although our knowledge of helminth molecular biology is improving through completed draft genome projects, there is limited detailed information on the molecular biology of Toxocara species. Here, transcriptomic sequencing of male and female adult T. canis and comparative analyses were conducted. For each sex, two-thirds (66-67%) of quality-filtered reads mapped to the gene set of T. canis, and at least five reads mapped to each of 16,196 (87.1%) of all 18,596 genes, and 321 genes were specifically transcribed in female and 1467 in male T. canis. Genes differentially transcribed between the two sexes were identified, enriched biological processes and pathways linked to these genes established, and molecules associated with reproduction and development predicted. In addition, small RNA pathways involved in reproduction were characterized, but there was no evidence for piwi RNA pathways in adult T. canis. The results of this transcriptomic study should provide a useful basis to support investigations of the reproductive biology of T. canis and related nematodes.2
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene - Volume 600, 5 February 2017, Pages 85-89
Journal: Gene - Volume 600, 5 February 2017, Pages 85-89
نویسندگان
Rong-Qiong Zhou, Guang-Xu Ma, Pasi K. Korhonen, Yong-Li Luo, Hong-Hong Zhu, Yong-Fang Luo, Robin B. Gasser, Qing-You Xia,