Contrast Stress Echocardiography for the Diagnosis of Coronary Artery Disease in Patients With Chest Pain but Without Acute Coronary Syndrome: Incremental Value of Myocardial Perfusion

The addition of MPI to standard DASE increased true-positive test results by >50% compared with WM criteria, with a nonsignificant difference in positive predictive value. Twenty-five patients were diagnosed with obstructive coronary artery disease thanks only to isolated MPI abnormalities; the cardiac origin of their chest pain would have been mistakenly “ruled out” on the basis of the absence of WM abnormalities.