Assessment of Temporal Heterogeneity and Regional Motion to Identify Wall Motion Abnormalities Using Treadmill Exercise Stress Three-Dimensional Echocardiography

Although the higher specificity of 3DE may represent avoidance of false-positives from off-axis imaging, the sensitivity of 3DE is insufficient for clinical use. Analysis of the temporal distribution of contraction may be more sensitive than 3D wall motion assessment for identification of ischemia at exercise 3DE.