کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5622622 1406183 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Featured ArticleMIND diet slows cognitive decline with aging
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
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Featured ArticleMIND diet slows cognitive decline with aging
چکیده انگلیسی

IntroductionThe Mediterranean and dash diets have been shown to slow cognitive decline; however, neither diet is specific to the nutrition literature on dementia prevention.MethodsWe devised the Mediterranean-Dietary Approach to Systolic Hypertension (DASH) diet intervention for neurodegenerative delay (MIND) diet score that specifically captures dietary components shown to be neuroprotective and related it to change in cognition over an average 4.7 years among 960 participants of the Memory and Aging Project.ResultsIn adjusted mixed models, the MIND score was positively associated with slower decline in global cognitive score (β = 0.0092; P < .0001) and with each of five cognitive domains. The difference in decline rates for being in the top tertile of MIND diet scores versus the lowest was equivalent to being 7.5 years younger in age.DiscussionThe study findings suggest that the MIND diet substantially slows cognitive decline with age. Replication of these findings in a dietary intervention trial would be required to verify its relevance to brain health.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Alzheimer's & Dementia - Volume 11, Issue 9, September 2015, Pages 1015-1022
نویسندگان
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