کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5623687 | 1406218 | 2016 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Featured ArticleADL disability and death in dementia in a French population-based cohort: New insights with an illness-death model Featured ArticleADL disability and death in dementia in a French population-based cohort: New insights with an illness-death model](/preview/png/5623687.png)
IntroductionTransition to bathing or dressing disability is a milestone in the evolution of dementia. We examined the transition to disability in these specific activities and considered death to be a competitive event and age and sex to be prognostic factors.MethodsFrom a large cohort of 570 incident dementia cases screened in two prospective population-based cohorts, the Paquid study, and the Three-City study, we estimated the probabilities of remaining nondisabled, becoming disabled in bathing or dressing, or dying after the diagnosis using an illness-death model.ResultsOn average, approximately half of the period (3 years) of living with dementia was free of disability. In women, a higher survival rate was associated with an average of 1 additional year with disability.DiscussionThe joint prediction of death and disability in dementia by an illness-death model gives original and useful parameters for the prognosis and management of dementia.
Journal: Alzheimer's & Dementia - Volume 12, Issue 8, August 2016, Pages 909-916