کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5638058 1583274 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Patterns of non-syndromic permanent tooth agenesis in a large orthodontic population
ترجمه فارسی عنوان
الگوهایی از آگنز دندان دائمی غیر سندرومیک در جمعیت ارتودنسی بزرگ
کلمات کلیدی
آگنز دندان، غیر سندرمیک، دندان دائمی، بیماران ارتودنسی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی


- Patterns of non-syndromic permanent tooth agenesis in 414 subjects.
- Symmetric agenesis patterns were commonly observed.
- In cases with 1 or 2 missing teeth, variation was limited to 27.8%.
- An incisor/premolar agenesis pattern was often prevalent in isolated form (59.0%).
- Particular genetic, epigenetic and/or environmental factors control tooth formation.

ObjectiveThe aim of this study is to explore patterns of non-syndromic permanent tooth agenesis in a large orthodontic patient group.DesignA record review was performed in various orthodontic clinics to identify white patients with non-syndromic permanent tooth agenesis, excluding 3rd molars. Four hundred and fourteen subjects fulfilled the inclusion criteria.ResultsIn the 414 subjects with tooth agenesis, approximately 70% presented 1-2 missing teeth. Symmetric agenesis patterns were often observed in the sample (by jaw, by side, or crossed quadrants), with prevalence approaching 30% for cases with contralateral tooth agenesis within a jaw. In cases with 1 or 2 missing teeth, from the total number of potential tooth agenesis patterns in the sample, a certain part was evident, limiting the variation to 27.8% (44/158). In the entire sample, both in the maxilla and the mandible a certain incisor/premolar agenesis phenotype was observed in 59.0% of cases in isolated form.ConclusionsAlthough there was variation in the tooth agenesis patterns, our findings suggest the involvement of particular genetic, epigenetic, and/or environmental factors in the formation of the entire dentition, which often lead to specific tooth agenesis phenotypes in cases where this process is disrupted.The present study provides a comprehensive categorization of orthodontic cases with tooth agenesis and can assist in planning future epidemiological and genetic studies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Oral Biology - Volume 79, July 2017, Pages 42-47
نویسندگان
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