Biological activity of glatiramer acetate on Treg and anti-inflammatory monocytes persists for more than 10Â years in responder multiple sclerosis patients

While NK, CD4 and CD8 T-cells did not show any significant differences among groups over time, we demonstrated that GA increased the anti-inflammatory monocytes and restored the Treg level in both GA-treated groups. Both these effects are a characteristic of responder patients and are observed not just in short-term but even after as long as a decade of GA treatment.