Pseudomonas aeruginosa quorum sensing modulates immune responses: An updated review article

- Bacteria use quorum sensing to enhance their survival in the hosts.
- Pseudomonas aeruginosa uses LasI/LasR and RhlI/RhlR systems for quorum sensing.
- The signaling molecules from the quorum sensing induce/stimulate immune responses.
- Pseudomonas aeruginosa uses quorum sensing molecules to attenuate immune responses.

Pseudomonas aeruginosa is an opportunistic bacterium which induces some complications in immunocompromised patients. Pseudomonas aeruginosa is a quorum-sensing using bacterium which regulates its genes expression. The bacterium uses two famous pathways for quorum sensing entitled LasI/LasR and RhlI/RhlR systems. It has been documented that the bacteria which use quorum sensing are able to overcome immune responses. This review article aims to present recent information regarding the effects of Pseudomonas aeruginosa quorum sensing systems on the host immune responses.