کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5670402 1408009 2016 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Immune memory in invertebrates
ترجمه فارسی عنوان
حافظه ایمنی در بی مهرگان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
چکیده انگلیسی


- Evidence for innate immune memory (or 'priming') in invertebrates is increasing.
- This article provides a detailed review of studies on invertebrate immune memory.
- Up to now, studies have focussed on Arthropods, while evidence for other taxa is fragmentary.
- Hypothesized molecular mechanisms for immune memory differ among invertebrate taxa.

Evidence for innate immune memory (or 'priming') in invertebrates has been accumulating over the last years. We here provide an in-depth review of the current state of evidence for immune memory in invertebrates, and in particular take a phylogenetic viewpoint. Invertebrates are a very heterogeneous group of animals and accordingly, evidence for the phenomenon of immune memory as well as the hypothesized molecular underpinnings differ largely for the diverse invertebrate taxa. The majority of research currently focuses on Arthropods, while evidence from many other groups of invertebrates is fragmentary or even lacking. We here concentrate on immune memory that is induced by pathogenic challenges, but also extent our view to a non-pathogenic context, i.e. allograft rejection, which can also show forms of memory and can inform us about general principles of specific self-nonself recognition. We discuss definitions of immune memory and a number of relevant aspects such as the type of antigens used, the route of exposure, and the kinetics of reactions following priming.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Immunology - Volume 28, Issue 4, August 2016, Pages 328-342
نویسندگان
, ,