کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5674467 | 1408234 | 2017 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Hypoglycémie paranéoplasique : les espoirs d'une documentation physiopathologique
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماری های عفونی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Hypoglycémie paranéoplasique : les espoirs d'une documentation physiopathologique Hypoglycémie paranéoplasique : les espoirs d'une documentation physiopathologique](/preview/png/5674467.png)
چکیده انگلیسی
Doege-Potter syndrome is a paraneoplastic syndrome characterized by non-islet cell tumor hypoglycemia secondary to a solitary fibrous tumor. These tumors are rare and usually asymptomatic. The syndrome of hypoglycemia is seen in less than 5% of the cases, and the associated tumors are large with a high mitotic rate. The cause of hypoglycemia is related to insulin-like growth factors produced by these tumors called “big” IGF-2. Several biological tests can demonstrate the increase of “big” IGF-2 plasma levels confirming the diagnosis of non-islet cell tumor induced hypoglycemia. The diagnosis is suggested by imaging but diagnostic confirmation is provided by the surgery, which remains the treatment of choice. Resection in many cases is the cure leading to hypoglycemia resolution. Recurrences and malignant transformations are possible which imposes a long-term monitoring. We report a case with relapsed malignant pleural fibrous tumor for which the pathophysiological mechanism of hypoglycemia could be documented as a paraneoplastic syndrome.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revue de Pneumologie Clinique - Volume 73, Issue 3, June 2017, Pages 140-145
Journal: Revue de Pneumologie Clinique - Volume 73, Issue 3, June 2017, Pages 140-145
نویسندگان
A. Villemain, O. Menard, D. Mandry, J. Siat, J.-M. Vignaud, Y. Martinet, A. Tiotiu,