کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5675033 1594209 2017 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Genome sequence variation among isolates of monkey B virus (Macacine alphaherpesvirus 1) from captive macaques
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ویروس شناسی
پیش نمایش صفحه اول مقاله
Genome sequence variation among isolates of monkey B virus (Macacine alphaherpesvirus 1) from captive macaques
چکیده انگلیسی
Complete genome sequences of 19 strains of monkey B virus (Macacine alphaherpesvirus 1; BV) isolated from several macaque species were determined. A low level of sequence variation was present among BV isolates from rhesus macaques. Most variation among BV strains isolated from rhesus macaques was located in regions of repetitive or quasi-repetitive sequence. Variation in coding sequences (polypeptides and miRNAs) was minor compared to regions of non-coding sequences. Non-coding sequences in the long and short repeat regions of the genome did however exhibit islands of conserved sequence. Oral and genital isolates from a single monkey were identical in sequence and varied only in the number of iterations of repeat units in several areas of repeats. Sequence variation between BV isolates from different macaque species (different BV genotypes) was much greater and was spread across the entire genome, confirming the existence of different genotypes of BV in different macaque species.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Virology - Volume 508, August 2017, Pages 26-35
نویسندگان
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