Dosimetric Comparison of Conventional Radiograph- and Three-dimensional Computed Tomography-based Planning using Dose Volume Indices for Partial Breast Intraoperative Implants

Objective dosimetric evaluation on three-dimensional computed tomography confirms its superiority over conventional two-dimensional radiograph-based planning in terms of a reduction in normal breast irradiated with the prescription dose and improvement in conformity. Interactive graphical optimisation based on the target volume in computed tomography further improves conformity with a reduction in dose homogeneity. The use of dose volume indices allows the comparison of different plans and can be used as a tool to correlate dosimetric with clinical outcome.