کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5725945 | 1411561 | 2017 | 6 صفحه PDF | دانلود رایگان |
To determine the lowest CT radiation dose-level at maintained image-quality and high sensitivity for detection of pulmonary-nodules in obesity. Single-energy CT with tin-filtration was performed in a chest-phantom with solid pulmonary-nodules simulating over-weight and obesity. CTDIvol of the standard-protocol was 0.41 mGy, subsequent scans were obtained at 1/2 and 1/4 dose-levels. Images were reconstructed using FBP and advanced-modeled iterative reconstruction (ADMIRE). Noise, image-quality, and sensitivity for nodule-detection were assessed. Noise was significantly reduced with ADMIRE (standard-dose: 73%; 1/2 dose: 73%; 1/4 dose: 71.2%; p < 0.001) compared to FBP. Image-quality was diagnostic for all images reconstructed with ADMIRE5. Sensitivity for nodule-detection was 100% at 1/2 and 1/4 dose-level for the phantom simulating over-weight and 97.37% (1/2 dose-level) and 81.58% (1/4 dose-level) for the phantom simulating obesity using ADMIRE5. In conclusion, single-energy CT with tin-filtration and ADMIRE shows potential for dose reduction in a phantom experiment down to 0.1 mGy in over-weight and 0.21 mGy obese subjects, while image quality and sensitivity for detection of solid pulmonary nodules remains high.
Journal: Current Problems in Diagnostic Radiology - Volume 46, Issue 3, MayâJune 2017, Pages 204-209