Radiological assessment of the breast following enhancement with Macrolane: Managing the challenges

- Macrolane VRF®, a biodegradable, stabilized hyaluronic acid gel, was used for breast enhancement 2008-2012.
- Even after more than 4 years, small amounts of Macrolane can still be visible on magnetic resonance imaging (MRI) or ultrasound in some patients similar to permanent implants, the presence of Macrolane gel may interfere with interpretation of mammography.
- Knowledge of the product's appearance on radiological assessment of breasts following Macrolane treatment is therefore required.
- It is possible to assess the vast majority of patients using a combination of digital mammography and ultrasonography examination.

Macrolane VRF®, a biodegradable, stabilized hyaluronic acid gel, was used for breast enhancement 2008-2012. Similar to permanent implants, the presence of Macrolane gel may interfere with interpretation of mammography. This short communication aims to provide a guide to the appearance of Macrolane on radiology examination (including mammography, ultrasound and magnetic resonance imaging) and aid selection of the most appropriate imaging modality to facilitate breast examination in women who have undergone Macrolane breast enhancement.