کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5726258 1609726 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Research papersDiagnostic accuracy of different magnetic resonance imaging sequences for detecting local tumor progression after radiofrequency ablation of hepatic malignancies
ترجمه فارسی عنوان
دقت تشخیصی توالی های تصویربرداری رزونانس مغناطیسی مختلف برای تشخیص پیشرفت تومور محلی پس از تخریب رادیوفرکانس های بدخیمی های کبدی
کلمات کلیدی
دقت تشخیصی تصویربرداری رزونانس مغناطیسی، فرسایش بسامد رادیویی، بدخیمی های کبدی، پیشرفت تومور محلی، تصادفات تصادفی،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی رادیولوژی و تصویربرداری
چکیده انگلیسی


- Unenhanced T1-FLASH-2D is an essential sequence for RFA follow-up imaging.
- Diagnostic confidence depends on the individual observers' experience.
- Cholestasis and vessels adjacent to ablation zone can cause false-positive rating.
- A hepatic abscess can mimic local recurrence in all sequences.

ObjectiveTo evaluate the diagnostic accuracy of the individual sequences of a clinical routine liver MRI protocol for the detection of local tumour progression after radiofrequency (RF) ablation of hepatic malignancies.Material and methodsA cohort of 93 patients treated for 140 primary and secondary hepatic malignancies with RF ablation was assembled for this retrospective study. The cohort contained 31 cases of local tumour progression, which occurred 8.3 ± 6.2 months (range: 4.0-28.2 months) after treatment. All patients underwent clinical routine follow-up MRI at 1.5T including following sequences: unenhanced T1-weighted fast low angle shot (FLASH-2D), T2-weighted turbo-spin-echo sequence, contrast-enhanced (CE) T1-weighted volume-interpolated breath-hold examination (VIBE), diffusion-weighted imaging (DWI). Follow-up was 32.7 ± 22.5 months (range: 4.0-138.3 months). Two readers independently evaluated the individual sequences separately for signs of local tumour progression. Diagnostic confidence was rated on a 4-point scale. Inter-reader agreement was assessed with Coheńs kappa. Long-term follow-up and histological specimen served as standard of reference.ResultsBoth readers reached the highest sensitivity for detection of local tumour progression with unenhanced T1-FLASH 2D (88.2% and 94.1%, respectively) and the highest specificity with CE T1-VIBE (96.2% and 97.2%, respectively). Highest inter-reader agreement was reached with T1-FLASH-2D (kappa = 0.83). Typical pitfalls for false-positive diagnoses were focal cholestasis and vasculature adjacent to the ablation zone. Diagnostic confidence was highest with CE T1-VIBE for reader 1 and DWI for reader 2.ConclusionUnenhanced T1-FLASH-2D is an essential sequence for follow-up imaging after tumour ablation with a high sensitivity for detection of local progression and a high inter-reader agreement.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Radiology - Volume 94, September 2017, Pages 85-92
نویسندگان
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