کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5726331 | 1609730 | 2017 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Repeated surgeries in invasive lobular breast cancer with preoperative MRI: Role of additional carcinoma in situ and background parenchymal enhancement Repeated surgeries in invasive lobular breast cancer with preoperative MRI: Role of additional carcinoma in situ and background parenchymal enhancement](/preview/png/5726331.png)
ObjectivesAnalysing the influence of additional carcinoma in situ (CIS) and background parenchymal enhancement (BPE) in preoperative MRI on repeated surgeries in patients with invasive lobular carcinoma (ILC) of the breast.MethodsRetrospective analysis of 106 patients (mean age 58.6 ± 9.9 years) with 108 ILC. Preoperative tumour size as assessed by MRI, mammography and sonography was recorded and compared to histopathology. In contrast-enhanced MRI, the degree of BPE was categorised by two readers. The influence of additionally detected CIS and BPE on the rate of repeated surgeries was analysed.ResultsAdditional CIS was present in 45.4% of the cases (49/108). The degree of BPE was minimal or mild in 80% of the cases and moderate or marked in 20% of the cases. In 17 cases (15.7%) at least one repeated surgery was performed. In n = 15 of these cases, repeated surgery was performed after BCT (n = 9 re-excisions, n = 6 conversions to mastectomy), in n = 2 cases after initial mastectomy. The initial surgical procedure (p = 0.008) and additional CIS (p = 0.046) significantly influenced the rate of repeated surgeries, while tumour size, patient age and BPE did not (p = ns).ConclusionsAdditional CIS was associated with a higher rate of repeated surgeries, whereas BPE had no influence.
Journal: European Journal of Radiology - Volume 90, May 2017, Pages 181-187