کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5739692 | 1615864 | 2016 | 17 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A Bayesian approach to estimating the uncertainty in the distribution of Cronobacter spp. in powdered infant formula arising from microbiological criteria test outcomes
ترجمه فارسی عنوان
یک رویکرد بیزی برای برآورد عدم قطعیت در توزیع گونه های کرانوباکتر در فرمول شیر پودر که نتیجه آزمایشات معیارهای میکروبیولوژیکی است
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کلمات کلیدی
معیارهای میکروبیولوژی، کرونوباکتر، بیزی، ایمنی مواد غذایی، برنامه نمونه گیری، فرمول پودر نوزاد
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروبیولوژی و بیوتکنولوژی کاربردی
چکیده انگلیسی
The application of microbiological criteria related to foods has become well established for the protection of public health. Sampling plans will more likely detect a microorganism when the level of contamination is high. However, as the concentration of the microorganism drops, detection becomes more and more infrequent. Cronobacter spp. is an opportunistic pathogen that can occur infrequently and in low concentrations in powdered infant formula (PIF) with a distribution that is typically heterogeneous. This paper developed a Bayesian approach to quantify the uncertainty in the concentration of Cronobacter spp. clusters that may be present in a batch of PIF depending on the outcome of a sampling plan. Two approaches were developed. The first was a Bayesian methodology using a spreadsheet approach to develop the appropriate likelihood and posterior distributions based on an uninformed prior distribution. The second approach was similar but used an algebraic approach rather than a spreadsheet numerical approximation to characterise the uncertainty. Different sampling plans were considered based on the EC Microbiological Criteria for Cronobacter spp. When a zero positive test was the outcome of the sampling plans considered, the Bayesian analysis indicated that while the most likely outcome for all the sampling plans considered was zero clusters present, the analysis indicated that the true number of clusters present could be as high as several thousand clusters per tonne of powder depending on the sampling plan. The algebraic approach demonstrated that for zero or one positive tests, the uncertainty distribution could be approximated by a gamma distribution. Choice of the prior distribution influenced the level of uncertainty. The Bayesian approach demonstrates that even when zero positives are detected for a given sampling plan, there remains a considerable uncertainty in the true number of microorganisms that may be present undetected in a consignment of powder.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Microbial Risk Analysis - Volume 4, December 2016, Pages 36-42
Journal: Microbial Risk Analysis - Volume 4, December 2016, Pages 36-42
نویسندگان
Friedrich von Westerholt, Ursula Gonzales-Barron, Francis Butler,