کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5803919 | 1555695 | 2013 | 7 صفحه PDF | دانلود رایگان |
The present study was aimed to determine the levels of trace elements zinc, copper, iron, erythrocyte oxidant/anti-oxidant balance, vitamin C and β-carotene in dogs with generalized demodecosis. A total of 24 dogs with clinically established diagnosis of generalized demodecosis and 6 dogs as control were included in the study. In comparison to healthy control, zinc and copper levels were significantly (P < 0.01) lower in dogs with generalized demodecosis, whereas iron levels were significantly (P < 0.01) higher. Malondialdehyde (MDA) levels were significantly (P < 0.01) higher in diseased dogs whereas activity of superoxide dismutase (SOD) and catalase were significantly (P < 0.01) lower. β-carotene and vitamin C levels were significantly (P < 0.05) lower in diseased dogs when compared to healthy control. SOD activity was positively correlated with zinc (rs = 0.65, rs = 0.71 and P < 0.05) and copper (rs = 0.51, rs = 0.63 and P < 0.05) in both healthy and diseased dogs. MDA levels were negatively correlated with iron (rs = â0.49, rs = â0.78 and P < 0.05), β-carotene (rs = â0.26, P > 0.05; rs = â0.54, P < 0.05, respectively) in both healthy and diseased dogs and with SOD activity in diseased dogs only (rs = â0.68, P < 0.05). From the present study, it was concluded that generalized demodecosis in dogs is associated with significant alteration in trace elements and oxidant/anti-oxidant imbalance and this imbalance might be secondary to changes caused by demodectic mange.
Journal: Veterinary Parasitology - Volume 198, Issues 1â2, 15 November 2013, Pages 180-186