The role of 5-HT1A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: A possible antidepressant mechanism

► The antidepressant-like behavior induced by fish oil involves the serotoninergic system. ► 5-HT1A receptor and BDNF expression are involved in fish oil antidepressant effect. ► Early ω-3 supplementation presumably prevents psychopathologies in young adulthood.