Cellular uptake and degradation behaviour of biodegradable poly(ethylene glycol-graft-methyl methacrylate) nanoparticles crosslinked with dimethacryloyl hydroxylamine

Nanoparticles made of diacyl hydroxylamine-crosslinked PEGylated polymethacrylates differ from conventional biodegradable particles. They are hydrolyzable at pH ≥ 7 and their cellular uptake is strongly controlled by their surface charge.