کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5821762 | 1557812 | 2016 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Anti-herpesviral effects of a novel broad range anti-microbial quaternary ammonium silane, K21
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ویروس شناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Anti-herpesviral effects of a novel broad range anti-microbial quaternary ammonium silane, K21 Anti-herpesviral effects of a novel broad range anti-microbial quaternary ammonium silane, K21](/preview/png/5821762.png)
چکیده انگلیسی
We have created a novel quaternary ammonium silane, K21 through sol-gel chemistry, using an ethoxylated version of an organosilane quaternary ammonium compound and TetraEthyl Ortho Silicate (TEOS) as precursors. Previous studies using the precursor molecule quaternary ammonium compounds (QACs) and a methacryloxy version of K21, primarily designed for use in dental healthcare, have shown inhibited growth properties against several types of gram-positive and gram-negative bacteria including Escherichia coli, Streptococcus mutans, Actinomyces naeslundii and Candida albicans etc. Here we tested the effect of K21 on HSV-1, HHV-6A and HHV-7 in in vitro cell culture infection models. Our results show growth inhibitory effect of K21 on HSV-1, HHV-6A and HHV-7 infection.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Antiviral Research - Volume 131, July 2016, Pages 166-173
Journal: Antiviral Research - Volume 131, July 2016, Pages 166-173
نویسندگان
Nitish Gulve, Kirk Kimmerling, Allen D. Johnston, Gerhard R. Krueger, Dharam V. Ablashi, Bhupesh K. Prusty,