Effects of a combretastatin A4 analogous chalcone and its Pt-complex on cancer cells: A comparative study of uptake, cell cycle and damage to cellular compartments

A chalcone and its Pt-complex, while both anticancer active, were found to differ distinctly in uptake routes, selectivity for glioma over normal neural cells, efficiency in multi-drug resistant cancer cells, influence on cell cycle progression, and fragmentation of the Golgi apparatus.