Augmenter of liver regeneration improves therapeutic effect of hepatocyte homotransplantation in acute liver failure rats

► ALR increases the survival time of the engraftments. ► ALR inhibits the inflammatory injury of the engraftments and liver. ► ALR suppresses the immunological rejections and protects the engraftments. ► ALR overcomes the main limitations of intraperitoneal HCT. ► Co-treatment with ALR and HCT improves the survival rate of ALF rats.