Ethanol extracts from Hemerocallis citrina attenuate the decreases of brain-derived neurotrophic factor, TrkB levels in rat induced by corticosterone administration

Hemerocallis citrina Baroni (Liliaceae) has traditionally been used in the treatment of depression. Administration of the ethanol extract of H. citrina (HCE) (32.5, 65, 130 mg/kg) reversed the depression-like behaviors and up-regulated the BDNF and TrkB receptor expressions in rats induced by exogenous administration of the stress hormone corticosterone241.