کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5844036 | 1127511 | 2013 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Associate editor: M. BelvisiPhytochemicals: Countering risk factors and pathological responses associated with ischaemia reperfusion injury Associate editor: M. BelvisiPhytochemicals: Countering risk factors and pathological responses associated with ischaemia reperfusion injury](/preview/png/5844036.png)
Plant derived non-nutritive molecules, known as phytochemicals, have been investigated for their ability to provide protection against inflammation. Emerging studies of several vasculopathies (e.g. atherosclerosis, hypertension) provide novel data to support these anti-inflammatory effects and offer evidence for involvement of host pathways. Fundamental mechanisms of action are common amongst these compounds, and furthermore, the administration of these phytochemicals activates host defence pathways innately present to protect cells from oxidative stress. This review will elucidate the real benefit of therapeutic intervention with these phytochemicals for vasculopathies, and associated ischaemia reperfusion injury in both the heart and brain.
Journal: Pharmacology & Therapeutics - Volume 138, Issue 1, April 2013, Pages 38-45