Antipsychotic dose and diminished neural modulation: A multi-site fMRI study

► This study is an fMRI investigation of motor response to auditory stimuli. ► Data analysis was completed with independent component analysis. ► Patients with schizophrenia had less modulation in specific neural networks. ► Antipsychotic dose equivalents correlated with the diminished neural modulation. ► The motor tasks may be especially sensitive to the effect of antipsychotics.