An unblinded comparison of the clinical and cognitive effects of switching from first-generation antipsychotics to aripiprazole, perospirone or olanzapine in patients with chronic schizophrenia

► There was no difference in clinical effect between aripiprazole and perospirone or olanzapine. ► There was no difference in cognitive effect between aripiprazole and perospirone. ► There might be possible differences between aripiprazole and olanzapine in the profiles of the improvement effects on executive function, memory, and attention function.