کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5847319 1129667 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ReviewMechanisms of endothelial cell protection by hydroxycinnamic acids
ترجمه فارسی عنوان
بررسی مکانیسم های حفاظت از سلول های اندوتلیال توسط اسیدهای هیدروکسی سمی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی

An endothelial dysfunction generates a proatherogenic environment characterized by stimulating thrombus formation. Epidemiological studies have provided evidence of a protective role of healthy diets in the prevention of cardiovascular diseases. Hydroxycinnamic acids constitute abundant polyphenols in our diets as they are present in high levels in many widely consumed foods, such as fruit, vegetables and beverages. Therefore, it can be established that due to the hydroxycinnamic acid content (caffeic, chlorogenic, feluric and p-coumaric acids), fruit, vegetables and beverages contribute to endothelial protection (attenuates oxidative stress, improved nitric oxide bioavailability and decreased E-selectin, ICAM-1 and VCAM-1 expression, among others). In this article, we systematically examine the mechanisms of endothelium protection of hydroxycinnamic acids.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vascular Pharmacology - Volume 63, Issue 3, December 2014, Pages 155-161
نویسندگان
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