Reduced exposure evaluation of an Electrically Heated Cigarette Smoking System. Part 6: 6-day randomized clinical trial of a menthol cigarette in Japan

► Electrically heated cigarette smoking system compared to conventional cigarettes. ► Mainstream smoke constituents reduced in the electrically heated cigarette. ► Biomarkers of exposure confirmed reduced exposure in a randomized clinical trial. ► Reductions in exposure to selected smoke constituents approach smoking cessation. ► No clinically relevant adverse effects observed.