Mutagenic, cytotoxic, and genotoxic properties of tobacco smoke produced by cigarillos available on the Canadian market

► Filtered cigarillos dimensionally similar to cigarettes are growing in popularity. ► Unlike cigars, many such products are highly flavored and smoke can be inhaled. ► Little known about toxicity of cigarillo mainstream smoke (MSS) versus cigarette MSS. ► Used in vitro assays to determine MSS mutagenicity, cytotoxicity, and clastogenicity. ► Assays showed MSS from cigarillos was not less toxic than MSS from cigarettes.