کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5860634 | 1133211 | 2013 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Paeoniflorin protects human EA.hy926 endothelial cells against gamma-radiation induced oxidative injury by activating the NF-E2-related factor 2/heme oxygenase-1 pathway
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Paeoniflorin protects human EA.hy926 endothelial cells against gamma-radiation induced oxidative injury by activating the NF-E2-related factor 2/heme oxygenase-1 pathway Paeoniflorin protects human EA.hy926 endothelial cells against gamma-radiation induced oxidative injury by activating the NF-E2-related factor 2/heme oxygenase-1 pathway](/preview/png/5860634.png)
چکیده انگلیسی
⺠EA.hy926 endothelial cells were treated with Paeoniflorin prior to radiation. ⺠The cell apoptosis was inhibited while the cell viability was enhanced. ⺠Paeoniflorin reduced ROS and enhanced endogenous antioxidants in EA.hy926 cells. ⺠The protective effect of Paeoniflorin involved in activating the Nrf2/HO-1 pathway. ⺠Paeoniflorin offer a potential application in treating radiation-induced injury.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Toxicology Letters - Volume 218, Issue 3, 26 April 2013, Pages 224-234
Journal: Toxicology Letters - Volume 218, Issue 3, 26 April 2013, Pages 224-234
نویسندگان
Jing Yu, Xiaoyun Zhu, Xin Qi, Juanjuan Che, Bangwei Cao,