Modulation of the cellular redox status by the Alternaria toxins alternariol and alternariol monomethyl ether

► AOH and AME affect the redox status of HT29 cells. ► Activate the Nrf2/ARE pathway. ► But do not affect the level of fpg-sensitive sites in the DNA. ► Indicating that oxidative stress is not substantially contributing to the genotoxic properties.