Proteome of melamine urinary bladder stones and implication for stone formation

► We analysed the composition and proteome of melamine bladder stones of rat models. ► The stones are composed of predominant melamine and a few amount of proteins. ► The proteins had a wide range of MWs and 1051 proteins were identified. ► Most proteins are related to cell injury, metabolic processes and binding function. ► Proteins may play an important role in melamine bladder stone formation.