In vitro screening of synergistic ascorbate-drug combinations for the treatment of malignant mesothelioma

► Gemcitabine and epigallocatechin-3-gallate synergize with ascorbate on mesothelioma. ► Gemcitabine/ascorbate is a promising combined therapy for malignant mesothelioma. ► Epigallocatechin-3-gallate/ascorbate is another promising therapy for mesothelioma.