Octyl and dodecyl gallates induce oxidative stress and apoptosis in a melanoma cell line

► Octyl and dodecyl gallates were cytotoxic to B16F10 cells in a time dependent manner. ► Octyl and dodecyl gallates activated the caspase-3. ► Octyl and dodecyl gallates disrupted the mitochondrial potential. ► Octyl and dodecyl gallates increased the Bax and decreased Bcl-2 proteins expression. ► Octyl and dodecyl gallates induced an oxidative stress in B16F10 cells.