Dietary carotenoid lutein protects against DNA damage and alterations of the redox status induced by cisplatin in human derived HepG2 cells

► Lutein-abundant antioxidant carotenoid in the diet. ► Safety use of lutein. ► Cisplatin induces DNA-instability and oxidative damage of macromolecules. ► Lutein counteracts the adverse effects of cisplatin. ► HepG2 cells is better than other cell lines because present detoxifying drug system.