کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5888773 | 1568127 | 2016 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Difference in the trajectory of change in bone geometry as measured by hip structural analysis in the narrow neck, intertrochanteric region, and femoral shaft between men and women following hip fracture
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کلمات کلیدی
HSABMDBHSDXAIPWCSA - ایالات مؤتلفهٔ آمریکاHip structural analysis - تجزیه و تحلیل ساختاری هیپBone mineral density - تراکم معدنی استخوانdual-energy X-ray absorptiometry - جذب اندازه گیری اشعه ایکس دوگانه انرژیFracture prevention - جلوگیری از شکستگیAging - سالخوردگیFemoral shaft - شفت فمورالOuter diameter - قطر خارجیsection modulus - مدول بخشcross-sectional area - مقطع عرضیBuckling ratio - نسبت خم شدنwee - وایOsteoporosis - پوکی استخوان
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Prior studies have shown that women have declines in bone structure and strength after hip fracture, but it is unclear whether men sustain similar changes. Therefore, the objective was to examine sex differences in proximal femur geometry following hip fracture. Hip structural analysis was used to derive metrics of bone structure and strength: aerial bone mineral density, cross-sectional bone area (CSA), cortical outer diameter, section modulus (SM), and buckling ratio (BR) from dual-energy x-ray absorptiometry scans performed at baseline (within 22 days of hospital admission), two, six, or twelve months after hip fracture in men and women (n = 282) enrolled in the Baltimore Hip Studies 7th cohort. Weighted estimating equations were used to evaluate sex differences at the narrow neck (NN), intertrochanteric (IT), and femoral shaft (FS). Men had significantly different one year NN changes compared to women in CSA: â 6.33% (â 12.47, â 0.20) vs. 1.37% (â 3.31, 6.43), P = 0.049; SM: â 4.98% (â 11.08, 1.10) vs. 3.94% (â 2.51, 10.42), P = 0.042; and BR: 7.50% (0.65, 14.36) vs. â 1.20% (â 6.41, 4.00), P = 0.044. One year IT changes displayed similar patterns, but the sex differences were not statistically significant for CSA: â 4.07% (â 10.83, 2.67) vs. 0.41% (â 3.41, 4.24), P = 0.252; SM: â 4.78% (â 12.10, 5.53) vs. -0.31 (â 4.74, 4.11), P = 0.287; and BR: 4.59% (â 0.65, 9.84) vs. 1.52% (â 4.23, 7.28), P = 0.425. Differences in FS geometric parameters were even smaller in magnitude and not significantly different by sex. Women generally experienced non-significant increases in bone tissue and strength following hip fracture, while men had structural declines that were statistically greater at the NN region. Reductions in the mechanical strength of the proximal femur after hip fracture could put men at higher risk for subsequent fractures of the contralateral hip.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bone - Volume 92, November 2016, Pages 124-131
Journal: Bone - Volume 92, November 2016, Pages 124-131
نویسندگان
Alan M. Ph.D., M.P.H., Michelle Ph.D., Denise Ph.D., J. Richard Ph.D., Gregory E. P.T., Ph.D., Thomas J. Sc.D., Jay Ph.D., M.S.Hyg, Marc C. M.D., M.P.H.,