کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5890176 | 1568153 | 2014 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Metabolic syndrome reduces bone mineral density in overweight adolescents
ترجمه فارسی عنوان
سندرم متابولیک تراکم استخوان را در نوجوانان اضافه وزن کاهش می دهد
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کلمات کلیدی
IDFSBPHDLCDBPBMCBMDDXABone mineral density - تراکم معدنی استخوانWaist circumference - دور کمرInternational Diabetes Federation - دیابت بین المللی دیابتMetabolic syndrome - سندرم متابولیکMetabolic syndrome X - سندرم متابولیک Xbody mass index - شاخص توده بدنBMI - شاخص توده بدنیdiastolic blood pressure - فشار خون دیاستولیکsystolic blood pressure - فشار خون سیستولیکMETS - متسBone mineral content - محتوای مواد معدنی استخوانAdolescents - نوجوانیHypertriglyceridemia - هیپرتریگلیسریدمیAbdominal obesity - چاقی شکم
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
چکیده انگلیسی
Growing concern has focused on the occurrence of metabolic syndrome (MetS) and its effects on bone mass. There is little information available in the literature concerning the relationship between MetS and BMD in adolescents. The aim of this study was to evaluate the effects of MetS and its components on bone mineral density (BMD) in overweight adolescent boys and girls. This cross-sectional study assessed 271 overweight adolescents with or without MetS (age 10 to 16 years). Anthropometric and biochemical tests were performed. Lumbar spine, proximal femur and total and subtotal body BMD values were obtained by bone densitometry with dual-energy X-ray absorptiometry. MetS was observed in 14% of the adolescents. Overweight adolescents of both genders who were positive for MetS presented with significant decreases in BMD (g/cm2/kg bodyweight) at all sites evaluated (p < 0.01). Female adolescents with large waist circumference, low HDLc, hypertriglyceridemia and high blood pressure showed significant reductions in BMD at all sites evaluated (p < 0.01) and, with the exception of increased triglycerides (which had no effect on BMD, p > 0.05), the same pattern was observed in male adolescents. Linear regression analyses revealed that waist circumference was negatively correlated with BMD in both genders and that triglycerides were negatively correlated with BMD only in female adolescents. Our results suggest that overweight adolescents with MetS have lower BMD than adolescents without MetS. Among all MetS components measured, increased waist circumference had the strongest relationship with reductions in BMD.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bone - Volume 66, September 2014, Pages 1-7
Journal: Bone - Volume 66, September 2014, Pages 1-7
نویسندگان
Valéria Nóbrega da Silva, Tamara Beres Lederer Goldberg, Luciana Nunes Mosca, Anapaula da Conceição Bisi Rizzo, Altamir dos Santos Teixeira, José Eduardo Corrente,