Relationship between vitamin D deficiency and bone fragility in sickle cell disease: A cohort study of 56 adults

► Vitamin D deficiency and fractures are highly prevalent in adult sickle cell disease patients. ► An increase risk of fractures was found in patients with very low vitamin D status. ► No correlation was found between bone mineral density and vitamin D status. ► Vitamin D supplementation should be part of the routine care of these patients.