The immune system and developmental programming of brain and behavior

► The nervous, endocrine, and immune systems communicate during health and disease. ► Cytokine dysregulation is linked to several diseases and neuropsychiatric disorders. ► Immune molecules and microglia are critical for normal brain development. ► Perinatal stressors may cause neuroimmune dysregulation and behavioral disorders. ► Microglia may present a novel target for interventions.