کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5904524 1158005 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Coffee polyphenols improve peripheral endothelial function after glucose loading in healthy male adults
ترجمه فارسی عنوان
پلی فنول قهوه پس از بارگذاری گلوکز در بزرگسالان سالم مردان، عملکرد اندوتلیال محیطی را بهبود می بخشد
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
چکیده انگلیسی
Brewed coffee is a widely consumed beverage, and many studies have examined its effects on human health. We investigated the vascular effects of coffee polyphenols (CPPs), hypothesizing that a single ingestion of CPP during glucose loading would improve endothelial function. To test this hypothesis, we conducted a randomized acute clinical intervention study with crossover design and measured reactive hyperemia index (RHI) to assess the acute effects of a 75-g glucose load with CPP in healthy, nondiabetic adult men. Blood glucose and insulin levels were elevated after glucose loading with and without CPP, with no significant differences between treatments. The RHI did not significantly decrease after glucose loading without CPP. With CPP, however, RHI significantly (P < .05) increased over baseline after glucose loading. The difference between treatments was statistically significant (P < .05). No significant changes were observed in an oxidative stress marker after glucose loading with or without CPP. These findings suggest that a single ingestion of CPP improves peripheral endothelial function after glucose loading in healthy subjects.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition Research - Volume 34, Issue 2, February 2014, Pages 155-159
نویسندگان
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