کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5913043 1161856 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Whole-genome sequencing to control antimicrobial resistance
ترجمه فارسی عنوان
توالی کامل ژنوم برای کنترل مقاومت ضد میکروبی
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
چکیده انگلیسی
Following recent improvements in sequencing technologies, whole-genome sequencing (WGS) is positioned to become an essential tool in the control of antibiotic resistance, a major threat in modern healthcare. WGS has already found numerous applications in this area, ranging from the development of novel antibiotics and diagnostic tests through to antibiotic stewardship of currently available drugs via surveillance and the elucidation of the factors that allow the emergence and persistence of resistance. Numerous proof-of-principle studies have also highlighted the value of WGS as a tool for day-to-day infection control and, for some pathogens, as a primary diagnostic tool to detect antibiotic resistance. However, appropriate data analysis platforms will need to be developed before routine WGS can be introduced on a large scale.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Trends in Genetics - Volume 30, Issue 9, September 2014, Pages 401-407
نویسندگان
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