Interfacial and micellar properties of mixed systems of tricyclic antidepressant drugs with polyoxyethylene alkyl ether surfactants

- Micellar and interfacial studies of amphiphilic drugs with nonionic surfactants.
- Drug-surfactant mixtures show improved surface active properties.
- Synergism is observed in all mixed systems.
- Hydrophobicity plays an important role in micellization.