کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
594534 | 1453983 | 2011 | 8 صفحه PDF | دانلود رایگان |

Fabrication of vesicles with the diameter of 4–30 μm was achieved by mixing hydrophobic nonionic surfactant (Span 65) with a poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymer (Pluronic P123) in aqueous solutions at room temperature. Ring-shaped structure of the Pluronic P123/Span 65 mixture assemblies was confirmed by fluorescence microscopy. The presence of internal aqueous phase in the Pluronic P123/Span 65 mixture assemblies was determined by measuring the entrapment efficiency of calcein using fluorescence spectroscopy. On the other hand, Pluronic P123/Span 60 mixture system formed wire-like assemblies but not vesicles.
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► Vesicle formation from Pluronic P123/Span 65 mixture in water.
► Wire-like assemblies formed from Pluronic P123/Span 60 mixture in water.
► Ring-shaped structure of Pluronic P123/Span 65 mixture assemblies observed by fluorescence microscopy.
► Wire-like assemblies of Pluronic P123/Span 60 mixture observed by cryo-transmission electron microscopy.
► Internal aqueous phase of Pluronic P123/Span 65 mixture vesicles confirmed by measuring the entrapment efficiency of calcein.
Journal: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Volume 389, Issues 1–3, 20 September 2011, Pages 82–89