The effect of LDLR-negative genotype on CT coronary atherosclerosis in asymptomatic statin treated patients with heterozygous familial hypercholesterolemia

► The extent of CT coronary atherosclerosis is higher in LDLR-negative mutations. ► The coronary plaque burden varied substantially in all LDLR mutational groups. ► CT could be helpful for the assessment of individual plaque-associated risk.