Dose-dependent effects of short term atorvastatin treatment on arterial wall properties and on indices of left ventricular remodeling in ischemic heart failure

► We studied the effect of short term atorvastatin treatment in ischemic HF patients. ► 40 mg/d of atorvastatin improved endothelial function and arterial stiffness. ► 40 mg/d of atorvastatin improved indices of left ventricular remodeling and adhesion molecules. ► The effects of atorvastatin on indices of arterial function are dose dependent. ► Patients with increased TC levels are prone to benefitted more from atorvastatin