Giant xanthomas associated with severe mixed dyslipidemia and arteriosclerotic vascular disease: A case report

- Giant xanthomas on ankle and knee
- Severe dyslipidemia (25 mmol/L triglycerides, 15.75 mmol/L cholesterol)
- Absence of xanthelasma, corneal arcus, tendinous, or aponeurotic xanthomas
- Symptomatic atherosclerotic disease (coronary and femoral arteries)
- No obvious etiology despite extensive biochemistry and genetic investigations

The report describes a case of mixed hyperlipoproteinemia in a 64-year-old patient presenting a serum hypertriglyceridemia at 25 mmol/L and hypercholesterolemia at 15.75 mmol/L, giant xanthomas and symptomatic atherosclerotic disease.