کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5996371 1180662 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Higher visceral to subcutaneous fat ratio is associated with small intestinal bacterial overgrowth
ترجمه فارسی عنوان
نسبت به چربی زیر جلدی بیشتر نسبت به افزایش بیش از اندازه باکتری های روده ای ارتباط دارد
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی


- Small intestinal bacterial overgrowth (SIBO) is associated with visceral fat deposition.
- Patients with SIBO may be at increased risk for cardiovascular complications.
- Patients with SIBO may benefit from tight control of metabolic syndrome.

Background and AimsThere is a lack of studies evaluating the association between small intestinal bacterial overgrowth (SIBO) and abdominal fat. The aim of this study was to evaluate whether visceral fat area (VFA), subcutaneous fat area (SFA) or visceral to subcutaneous fat ratio (VFA/SFA ratio) were associated with SIBO.Methods and ResultsIn this case-control study, 152 eligible patients submitted to glucose hydrogen/methane breath test who also had computed tomography (CT) of the abdomen performed were included. Clinical and demographic information was obtained. VFA and SFA were measured using Image J software at lumbar 3 level on CT cross-sectional image of the 152 patients included in this study, 68 patients (44.7%) tested positive for SIBO. In the univariate analysis, the presence of SIBO was associated with older age (65.2 ± 1.5 vs. 59.3 ± 1.5, p = 0.007); type 2 diabetes mellitus (33.8% vs. 17.9%; p = 0.019); hypertension (63.2% vs. 39.3%; p = 0.003); metabolic syndrome (85.3% vs. 64.3%; p = 0.003); and higher VFA/SFA ratio (1.0 ± 0.1 vs. 0.7 ± 0.1; p < 0.001). In multivariate analysis, metabolic syndrome (odds ratio [OR]: 2.5; 95% confidence interval [CI]: 1.1-5.7; p = 0.035) and higher VFA/SFA ratio (OR: 3.3; 95% CI: 1.6-7.2; p = 0.002) remained independently associated with SIBO.ConclusionThe presence of SIBO was found to be associated with high VFA/SFA ratio measured from cross-sectional CT image.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition, Metabolism and Cardiovascular Diseases - Volume 26, Issue 9, September 2016, Pages 773-777
نویسندگان
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