Novel forms of forgetting in temporal lobe epilepsy

► Temporal lobe epilepsy can present with recurrent episodes of transient amnesia. ► Onset in middle age and amnesia on awakening are typical of this presentation. ► Persistent impairment of remote autobiographical memory occurs in 2/3 of patients. ► Accelerated loss of information over hours-weeks occurs in 1/2 of patients. ► These interictal memory difficulties are not detected by standard memory tests.